Botulinum toxin treatment of facial myoclonus in suspected Rasmussen encephalitis

Nina Browner, Shaheda N. Azher, Joseph Jankovic

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

Patients with Rasmussen encephalitis (RE) may develop a variety of involuntary movements. We report a 26-year-old woman who presented with a 3-year history of progressive, continuous myoclonus of the left side of the face and left arm as well as left spastic hemiparesis. Magnetic resonance imaging of the brain showed right hemisphere and basal ganglia atrophy, and 24-hour electroencephalogram demonstrated diffuse slowing with random sharp waves in both hemispheres. An 18-fluoro-deoxy-glucose positron emission tomography scan indicated hypometabolism of the right cerebral hemisphere, including basal ganglia and thalamus. We successfully treated her myoclonus with injections of botulinum toxin A into the left zygomaticus muscle.

Original languageEnglish
Pages (from-to)1500-1502
Number of pages3
JournalMovement Disorders
Volume21
Issue number9
DOIs
StatePublished - Sep 2006
Externally publishedYes

Keywords

  • Botulinum toxin
  • Myoclonus
  • Rasmussen encephalitis

Fingerprint

Dive into the research topics of 'Botulinum toxin treatment of facial myoclonus in suspected Rasmussen encephalitis'. Together they form a unique fingerprint.

Cite this