Born in Bradford, a cohort study of babies born in Bradford, and their parents: Protocol for the recruitment phase

Pauline Raynor, Lelia Duley, Neil Small, Derek Tuffnell, Chris Wild, John Wright, Rebecca Airey, Shaheen Akhtar, Helen Brown, Jo Crompton, Jeff Davies, Stuart Emsley, Diane Farrar, Sarah Hepworth, Dawn Jankowicz, Will Johnson, Virginia Lodge, Trish McKinney, Sam Oddie, Sally Ann PearsonSunita Seal, Dagmar Waiblinger, Jane West, Katie Adamson, Ann Barratt, Carolyn Clover, Rizwana Lawrence, Maryam Riaz, Sameera Ali, Joan Bartle, Nicola Esgate, Jane Galbraith, Rizwana Kausir, Sairah Mahmood, Shaista Meer, Nicole Gibson, Rose Wall, Graham Law, Renée Mijal, Safa Moghul, Shasta Sarwar, Neil France, Elizabeth Smith, Miles Sykes, Barry Clarke, Chibvez Jaja-Wachuku, Mary Tolson, Piyush Shah, Robert West, Shahid Ali, Peter Dickson, Steve Ingleson, Robert Maden, Sue Nguyen, Sally Anne Pearson, Catherine Seal, Claire Seymour, Anita Sims, Michelle Turner, Cathy Woffendin, Noel Cameron, Raj Bhopal, George Davey-Smith, Allan House, Debbie Lawlor, David Leon, Andy Ness, Patricia McKinney

Research output: Contribution to journalArticlepeer-review

93 Scopus citations

Abstract

Background. Bradford, one of the most deprived cities in the United Kingdom, has a wide range of public health problems associated with socioeconomic deprivation, including an infant mortality rate almost double that for England and Wales. Infant mortality is highest for babies of Pakistani origin, who comprise almost half the babies born in Bradford. The Born in Bradford cohort study aims to examine environmental, psychological and genetic factors that impact on health and development perinatally, during childhood and subsequent adult life, and those that influence their parents' health and wellbeing. This protocol outlines methods for the recruitment phase of the study. Methods. Most Bradford women attend for antenatal care and give birth at the Bradford Royal Infirmary, which has approximately 5,800 births per year. Women are eligible for recruitment if they plan to give birth here. Babies born from March 2007 are eligible to participate, recruitment is planned to continue until 2010. Fathers of babies recruited are invited to participate. Women are usually recruited when they attend for a routine oral glucose tolerance test at 26-28 weeks gestation. Recruitment of babies is at birth. Fathers are recruited whenever possible during the antenatal period, or soon after the birth. The aim is to recruit 10,000 women, their babies, and the babies' fathers. At recruitment women have blood samples taken, are interviewed to complete a semi-structured questionnaire, weighed, and have height, arm circumference and triceps skinfold measured. Umbilical cord blood is collected at birth. Within two weeks of birth babies have their head, arm and abdominal circumference measured, along with subscapular and triceps skinfold thickness. Fathers self-complete a questionnaire at recruitment, have height and weight measured, and provide a saliva sample. Participants are allocated a unique study number. NHS numbers will be used to facilitate record linkage and access to routine data. A wide range of hospital and community sources is being accessed to provide data for the women and children. Data are checked for accuracy and consistency. Conclusion. Born in Bradford will increase understanding of the factors that contribute to health and wellbeing, and identify factors that influence differences in them between people of Pakistani and European origin.

Original languageEnglish
Article number327
JournalBMC Public Health
Volume8
DOIs
StatePublished - 2008
Externally publishedYes

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