Bone loss in thyroid disease: Role of low TSH and high thyroid hormone

Etsuko Abe; Li Sun; Jeffrey Mechanick; Jameel Iqbal; Kosj Yamoah; Ramkumarie Baliram; Ario Arabi; Baljit S. Moonga; Terry F. Davies; Mone Zaidi

doi:10.1196/annals.1402.062

Bone loss in thyroid disease: Role of low TSH and high thyroid hormone

Etsuko Abe, Li Sun, Jeffrey Mechanick, Jameel Iqbal, Kosj Yamoah, Ramkumarie Baliram, Ario Arabi, Baljit S. Moonga, Terry F. Davies, Mone Zaidi

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

33 Scopus citations

Abstract

More than 10% of postmenopausal women in the United States receive thyroid hormone replacement therapy and up to 20% of these women are over-replaced inducing subclinical hyperthyroidism. Because hyperthyroidism and post menopausal osteoporosis overlap in women of advancing age, it is urgent to understand the effect of thyroid hormone excess on bone. We can now provide results that not thyroid hormones but also TSH itself has an equally important role to play in bone remodeling.

Original language	English
Title of host publication	Skeletal Biology and Medicine, Part A
Subtitle of host publication	Aspects of Bone Morphogenesis and Remodeling
Publisher	Blackwell Publishing Inc.
Pages	383-391
Number of pages	9
ISBN (Print)	9781573316842
DOIs	https://doi.org/10.1196/annals.1402.062
State	Published - Nov 2007

Publication series

Name	Annals of the New York Academy of Sciences
Volume	1116
ISSN (Print)	0077-8923
ISSN (Electronic)	1749-6632

Keywords

Bone remodeling
Osteoporosis
Thyroid receptor

Access to Document

10.1196/annals.1402.062

Cite this

Abe, E., Sun, L., Mechanick, J., Iqbal, J., Yamoah, K., Baliram, R., Arabi, A., Moonga, B. S., Davies, T. F., & Zaidi, M. (2007). Bone loss in thyroid disease: Role of low TSH and high thyroid hormone. In Skeletal Biology and Medicine, Part A: Aspects of Bone Morphogenesis and Remodeling (pp. 383-391). (Annals of the New York Academy of Sciences; Vol. 1116). Blackwell Publishing Inc.. https://doi.org/10.1196/annals.1402.062

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abstract = "More than 10% of postmenopausal women in the United States receive thyroid hormone replacement therapy and up to 20% of these women are over-replaced inducing subclinical hyperthyroidism. Because hyperthyroidism and post menopausal osteoporosis overlap in women of advancing age, it is urgent to understand the effect of thyroid hormone excess on bone. We can now provide results that not thyroid hormones but also TSH itself has an equally important role to play in bone remodeling.",

keywords = "Bone remodeling, Osteoporosis, Thyroid receptor",

author = "Etsuko Abe and Li Sun and Jeffrey Mechanick and Jameel Iqbal and Kosj Yamoah and Ramkumarie Baliram and Ario Arabi and Moonga, {Baljit S.} and Davies, {Terry F.} and Mone Zaidi",

year = "2007",

month = nov,

doi = "10.1196/annals.1402.062",

language = "English",

isbn = "9781573316842",

series = "Annals of the New York Academy of Sciences",

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Abe, E, Sun, L, Mechanick, J, Iqbal, J, Yamoah, K, Baliram, R, Arabi, A, Moonga, BS, Davies, TF & Zaidi, M 2007, Bone loss in thyroid disease: Role of low TSH and high thyroid hormone. in Skeletal Biology and Medicine, Part A: Aspects of Bone Morphogenesis and Remodeling. Annals of the New York Academy of Sciences, vol. 1116, Blackwell Publishing Inc., pp. 383-391. https://doi.org/10.1196/annals.1402.062

Bone loss in thyroid disease: Role of low TSH and high thyroid hormone. / Abe, Etsuko; Sun, Li; Mechanick, Jeffrey et al.
Skeletal Biology and Medicine, Part A: Aspects of Bone Morphogenesis and Remodeling. Blackwell Publishing Inc., 2007. p. 383-391 (Annals of the New York Academy of Sciences; Vol. 1116).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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T1 - Bone loss in thyroid disease

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AU - Mechanick, Jeffrey

AU - Iqbal, Jameel

AU - Yamoah, Kosj

AU - Baliram, Ramkumarie

AU - Arabi, Ario

AU - Moonga, Baljit S.

AU - Davies, Terry F.

AU - Zaidi, Mone

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AB - More than 10% of postmenopausal women in the United States receive thyroid hormone replacement therapy and up to 20% of these women are over-replaced inducing subclinical hyperthyroidism. Because hyperthyroidism and post menopausal osteoporosis overlap in women of advancing age, it is urgent to understand the effect of thyroid hormone excess on bone. We can now provide results that not thyroid hormones but also TSH itself has an equally important role to play in bone remodeling.

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KW - Osteoporosis

KW - Thyroid receptor

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EP - 391

BT - Skeletal Biology and Medicine, Part A

PB - Blackwell Publishing Inc.

ER -

Bone loss in thyroid disease: Role of low TSH and high thyroid hormone

Abstract

Publication series

Keywords

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