Bone loss in thyroid disease: Role of low TSH and high thyroid hormone

Etsuko Abe, Li Sun, Jeffrey Mechanick, Jameel Iqbal, Kosj Yamoah, Ramkumarie Baliram, Ario Arabi, Baljit S. Moonga, Terry F. Davies, Mone Zaidi

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

12 Scopus citations


More than 10% of postmenopausal women in the United States receive thyroid hormone replacement therapy and up to 20% of these women are over-replaced inducing subclinical hyperthyroidism. Because hyperthyroidism and post menopausal osteoporosis overlap in women of advancing age, it is urgent to understand the effect of thyroid hormone excess on bone. We can now provide results that not thyroid hormones but also TSH itself has an equally important role to play in bone remodeling.

Original languageEnglish
Title of host publicationSkeletal Biology and Medicine, Part A
Subtitle of host publicationAspects of Bone Morphogenesis and Remodeling
PublisherBlackwell Publishing Inc.
Number of pages9
ISBN (Print)9781573316842
StatePublished - Nov 2007

Publication series

NameAnnals of the New York Academy of Sciences
ISSN (Print)0077-8923
ISSN (Electronic)1749-6632


  • Bone remodeling
  • Osteoporosis
  • Thyroid receptor


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