TY - JOUR
T1 - Bone, blood and semen lead in men with environmental and moderate occupational exposure
AU - Farias, Paulina
AU - Echavarria, Mirna
AU - Hernandez-Avila, Mauricio
AU - Villanueva, Carlos
AU - Amarasiriwardena, Chitra
AU - Hernandez, Leticia
AU - Aro, Antonio
AU - Hu, Howard
N1 - Funding Information:
This work was supported by funding from CONACyT, Mexico; the NIEHS/Superfund P42-ES05947 (with funding from the U.S. Environmental Protection Agency), NIEHS Center Grant 2 930 ES 00002 USA, The American British Cowdray Hospital and the Health Ministry, Mexico.
PY - 2005/2
Y1 - 2005/2
N2 - Lead (Pb) in blood, bone, and semen was measured in 162 to 186 environmentally exposed men from Mexico City, aged 19-48. Semen Pb was measured by inductively coupled plasma mass spectrometry, blood Pb by atomic absorption spectrometry and bone Pb by K X-ray fluorescence. Mean Pb levels in blood, semen, tibia (cortical) and patella (trabecular) bone were 12 μg/dl, 2.7 μg/1, 13 μg/g, and 20 μg/g, respectively. Semen Pb was determined by blood Pb and patella Pb. Determinants of higher tibia Pb were age, living near industry in which Pb is used, and a high occupational Pb exposure index. Higher patella Pb was predicted by age, higher traffic density near home, a high index of occupational exposure to Pb and a greater number of cigarettes smoked per day in the year prior to the study. Blood and bone Pb results are consistent with findings in other populations. Semen results provide new information on the semen-bone Pb relationship. Bone, especially trabecular one, proved to be a significant endogenous lead source for blood and semen burdens in reproductive aged men.
AB - Lead (Pb) in blood, bone, and semen was measured in 162 to 186 environmentally exposed men from Mexico City, aged 19-48. Semen Pb was measured by inductively coupled plasma mass spectrometry, blood Pb by atomic absorption spectrometry and bone Pb by K X-ray fluorescence. Mean Pb levels in blood, semen, tibia (cortical) and patella (trabecular) bone were 12 μg/dl, 2.7 μg/1, 13 μg/g, and 20 μg/g, respectively. Semen Pb was determined by blood Pb and patella Pb. Determinants of higher tibia Pb were age, living near industry in which Pb is used, and a high occupational Pb exposure index. Higher patella Pb was predicted by age, higher traffic density near home, a high index of occupational exposure to Pb and a greater number of cigarettes smoked per day in the year prior to the study. Blood and bone Pb results are consistent with findings in other populations. Semen results provide new information on the semen-bone Pb relationship. Bone, especially trabecular one, proved to be a significant endogenous lead source for blood and semen burdens in reproductive aged men.
KW - Blood lead
KW - Bone lead
KW - Environmental lead
KW - K X-ray fluorescence
KW - Semen lead
UR - http://www.scopus.com/inward/record.url?scp=17444401789&partnerID=8YFLogxK
U2 - 10.1080/09603120400018782
DO - 10.1080/09603120400018782
M3 - Article
C2 - 16028333
AN - SCOPUS:17444401789
SN - 0960-3123
VL - 15
SP - 21
EP - 31
JO - International Journal of Environmental Health Research
JF - International Journal of Environmental Health Research
IS - 1
ER -