TY - JOUR
T1 - Body dysmorphic disorder
T2 - A treatment synthesis and consensus on behalf of the International College of Obsessive-Compulsive Spectrum Disorders and the Obsessive Compulsive and Related Disorders Network of the European College of Neuropsychopharmacology
AU - Castle, David
AU - Beilharz, Francesca
AU - Phillips, Katharine A.
AU - Brakoulias, Vlasios
AU - Drummond, Lynne M.
AU - Hollander, Eric
AU - Ioannidis, Konstantinos
AU - Pallanti, Stefano
AU - Chamberlain, Samuel R.
AU - Rossell, Susan L.
AU - Veale, David
AU - Wilhelm, Sabine
AU - Van Ameringen, Michael
AU - Dell'Osso, Bernardo
AU - Menchon, Jose M.
AU - Fineberg, Naomi A.
N1 - Publisher Copyright:
© 2020 The Author(s). Published by Wolters Kluwer Health, Inc.
PY - 2021/3/1
Y1 - 2021/3/1
N2 - Body dysmorphic disorder (BDD) is characterized by a preoccupation with a perceived appearance flaw or flaws that are not observable to others. BDD is associated with distress and impairment of functioning. Psychiatric comorbidities, including depression, social anxiety, and obsessive-compulsive disorder are common and impact treatment. Treatment should encompass psychoeducation, particularly addressing the dangers associated with cosmetic procedures, and may require high doses of selective serotonin reuptake inhibitors∗ (SSRI∗) and protracted periods to establish full benefit. If there is an inadequate response to SSRIs, various adjunctive medications can be employed including atypical antipsychotics∗, anxiolytics∗, and the anticonvulsant levetiracetam∗. However, large-scale randomized controlled trials are lacking and BDD is not an approved indication for these medications. Oxytocin∗ may have a potential role in treating BDD, but this requires further exploration. Cognitive-behavioural therapy has good evidence for efficacy for BDD, and on-line and telephone-assisted forms of therapy are showing promise. CBT for BDD should be customized to address such issues as mirror use, perturbations of gaze, and misinterpretation of others' emotions, as well as overvalued ideas about how others view the individual.
AB - Body dysmorphic disorder (BDD) is characterized by a preoccupation with a perceived appearance flaw or flaws that are not observable to others. BDD is associated with distress and impairment of functioning. Psychiatric comorbidities, including depression, social anxiety, and obsessive-compulsive disorder are common and impact treatment. Treatment should encompass psychoeducation, particularly addressing the dangers associated with cosmetic procedures, and may require high doses of selective serotonin reuptake inhibitors∗ (SSRI∗) and protracted periods to establish full benefit. If there is an inadequate response to SSRIs, various adjunctive medications can be employed including atypical antipsychotics∗, anxiolytics∗, and the anticonvulsant levetiracetam∗. However, large-scale randomized controlled trials are lacking and BDD is not an approved indication for these medications. Oxytocin∗ may have a potential role in treating BDD, but this requires further exploration. Cognitive-behavioural therapy has good evidence for efficacy for BDD, and on-line and telephone-assisted forms of therapy are showing promise. CBT for BDD should be customized to address such issues as mirror use, perturbations of gaze, and misinterpretation of others' emotions, as well as overvalued ideas about how others view the individual.
KW - antipsychotics
KW - body dysmorphic disorder
KW - cognitive-behaviour therapy
KW - obsessive-compulsive disorder
KW - serotonin reuptake inhibitors
UR - http://www.scopus.com/inward/record.url?scp=85101896178&partnerID=8YFLogxK
U2 - 10.1097/YIC.0000000000000342
DO - 10.1097/YIC.0000000000000342
M3 - Review article
C2 - 33230025
AN - SCOPUS:85101896178
SN - 0268-1315
VL - 36
SP - 61
EP - 75
JO - International Clinical Psychopharmacology
JF - International Clinical Psychopharmacology
IS - 2
ER -