Blood pressure response to changes in serum ionized calcium during hemodialysis

J. C. Maynard, C. Cruz, M. Kleerekoper, N. W. Levin

Research output: Contribution to journalArticlepeer-review

78 Scopus citations

Abstract

The effect of an increasing serum ionized calcium concentration on blood pressure during hemodialysis was studied in a prospective cross-over trial. Twelve patients were dialyzed three times with a dialysate Ca concentration of 5.5 mg/dL and three times with one of 7.5 mg/dL. Dialysis with the high Ca dialysate was associated with less fall in the mean arterial pressure (p < 0.001). No statistically significant changes occurred in serum osmolality, body weight, or heart rate after dialysis at the two dialysate Ca levels. Increasing the Ca concentration in dialysate may protect against intradialytic hypotension in some patients.

Original languageEnglish
Pages (from-to)358-361
Number of pages4
JournalAnnals of Internal Medicine
Volume104
Issue number3
DOIs
StatePublished - 1986
Externally publishedYes

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