Blood pressure, memory, and electroconvulsive therapy

I. M. Zervas, A. Calev, L. Jandorf, M. Fink

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Blood pressure changes recorded during electroconvulsive therapy (ECT) in 23 psychiatric in-patients with major depressive disorders correlated with and predicted the degree of anterograde memory changes measured 48-72 h after ECT. The Randt memory test was the principal measure of memory change. A subgroup of older patients with cardiovascular illness received trimethaphan, a ganglionic blocker that impedes a hypertensive surge during the treatment. They did not differ in memory function from a younger subgroup that did not receive trimethaphan. Control of the hypertensive response in the older age group counterbalanced the additional memory dysfunction that was anticipated as a result of advanced age and cardiovascular pathology.

Original languageEnglish
Pages (from-to)14-22
Number of pages9
JournalConvulsive Therapy
Issue number1
StatePublished - 1993
Externally publishedYes


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