Abstract
Blood lymphocytes of infectious mononucleosis (IM) patients, unlike those obtained from healthy individuals, exhibit the following characteristics of activated T cells: (I) 'stable' E rosette formation; (2) natural attachment to various human normal and malignant cells; (3) sensitivity in vitro to the lytic effect of glucocorticoids. Although the IM T cells attach in vitro to all the human cells tested, they kill only the EBV genome carrying targets. The possibility is discussed that some of the activated T cells in IM result from a non-specific activation elicited by the T cells responding specifically to the EBV associated antigens.
Original language | English |
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Pages (from-to) | 153-158 |
Number of pages | 6 |
Journal | Journal of Clinical and Laboratory Immunology |
Volume | 3 |
Issue number | 3 |
State | Published - 1980 |