Blockmodels for connectome analysis

Daniel Moyer, Boris Gutman, Gautam Prasad, Joshua Faskowitz, Greg Ver Steeg, Paul Thompson

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

14 Scopus citations

Abstract

In the present work we study a family of generative network model and its applications for modeling the human connectome. We introduce a minor but novel variant of the Mixed Membership Stochastic Blockmodel and apply it and two other related model to two human connectome datasets (ADNI and a Bipolar Disorder dataset) with both control and diseased subjects. We further provide a simple generative classifier that, alongside more discriminating methods, provides evidence that blockmodels accurately summarize tractography count networks with respect to a disease classification task.

Original languageEnglish
Title of host publication11th International Symposium on Medical Information Processing and Analysis
EditorsJuan D. Garcia-Arteaga, Jorge Brieva, Natasha Lepore, Eduardo Romero
PublisherSPIE
ISBN (Electronic)9781628419160
DOIs
StatePublished - 2015
Externally publishedYes
Event11th International Symposium on Medical Information Processing and Analysis, SIPAIM 2015 - Cuenca, Ecuador
Duration: 17 Nov 201519 Nov 2015

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume9681
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X

Conference

Conference11th International Symposium on Medical Information Processing and Analysis, SIPAIM 2015
Country/TerritoryEcuador
CityCuenca
Period17/11/1519/11/15

Keywords

  • Connectomics
  • Diffusion Weighted Imaging
  • Random Network Models

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