Block the FAS, lose the fat

Charles V. Mobbs, Hideo Makimura

Research output: Contribution to journalShort surveypeer-review

68 Scopus citations


A small-molecular-weight drug originally developed to treat cancer produces sustained reduction in body weight in obese mice by a novel hypothalamic mechanism. The findings suggest new targets for the development of antiobesity drugs.

Original languageEnglish
Pages (from-to)335-336
Number of pages2
JournalNature Medicine
Issue number4
StatePublished - 2002
Externally publishedYes


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