Abstract
Many neurons, particularly inhibitory neurons in motor areas, express ion channels that cause them to fire rapidly and regularly without input. A paper now presents evidence that an inherited ataxia due to mutation in a P/Q-type calcium channel gene results from compromised pacemaking in cerebellar Purkinje neurons, suggesting a possible therapy.
| Original language | English |
|---|---|
| Pages (from-to) | 297-298 |
| Number of pages | 2 |
| Journal | Nature Neuroscience |
| Volume | 9 |
| Issue number | 3 |
| DOIs | |
| State | Published - Mar 2006 |
| Externally published | Yes |