Bleomycin for Treatment of Immune Cytopenia

E. A. Phillips, S. Kempin, L. Reich, B. Clarkson

Research output: Contribution to journalLetterpeer-review


To the Editor: In two patients with lymphomas in remission, immune cytopenia was successfully treated with bleomycin sulfate after conventional therapy failed. A 20-year-old man received radiation therapy to a mantle port in 1969, for treatment of clinical Stage IIB Hodgkin's disease. Over the next four years, he had three episodes of idiopathic thrombocytopenic purpura (ITP) and finally underwent splenectomy. The Hodgkin's disease involved the spleen. The splenic pedicle and para-aortic nodes were irradiated. Two years later thrombocytopenia recurred. A workup showed no evidence of Hodgkin's disease. The thrombocytopenia failed to respond to steroids, vinblastine, cyclophosphamide, or plasmapheresis. Because continuous. . . No extract is available for articles shorter than 400 words.

Original languageEnglish
Pages (from-to)1031
Number of pages1
JournalNew England Journal of Medicine
Issue number18
StatePublished - 1 May 1980
Externally publishedYes


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