BK virus: Discovery, epidemiology, and biology

Parmjeet Randhawa, Abhay Vats, Ron Shapiro, Karen Weck, Velma Scantlebury

Research output: Contribution to journalReview articlepeer-review

35 Scopus citations

Abstract

This article describes the discovery of BK virus in 1970 and chronicles the growing understanding of its epidemiology from a historical perspective. The biology of the virus is summarized with particular reference to mechanisms of host cell entry, maintenance of viral latency, and mechanisms of subsequent reactivation leading to clinical disease. The rudimentary nature of the current understanding of BKV is highlighted, and areas worthy of future investigation are identified.

Original languageEnglish
Pages (from-to)S19-S27
JournalGraft
Volume5
Issue numberSUPPL.
DOIs
StatePublished - Dec 2002
Externally publishedYes

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