Abstract
This article describes the discovery of BK virus in 1970 and chronicles the growing understanding of its epidemiology from a historical perspective. The biology of the virus is summarized with particular reference to mechanisms of host cell entry, maintenance of viral latency, and mechanisms of subsequent reactivation leading to clinical disease. The rudimentary nature of the current understanding of BKV is highlighted, and areas worthy of future investigation are identified.
Original language | English |
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Pages (from-to) | S19-S27 |
Journal | Graft |
Volume | 5 |
Issue number | SUPPL. |
DOIs | |
State | Published - Dec 2002 |
Externally published | Yes |