Abstract
A biomarker is a characteristic that can be used as an indicator of a biological state. A biomarker can be a clinical observation, laboratory test or an imaging parameter. In this review, we discuss the use of biomarkers in differentiating cardiac from noncardiac disease; predicting the prognosis of patients with heart failure, pulmonary hypertension and dilated cardiomyopathy; diagnosing subclinical cardiac involvement in muscular dystrophy and postchemotherapy cancer patients; detecting acute rejection following heart transplantation; diagnosing Kawasaki disease; aiding the management of postoperative cardiac patients; and managing both common (tetralogy of Fallot) and complex (single-ventricle physiology) congenital heart diseases.
Original language | English |
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Pages (from-to) | 943-963 |
Number of pages | 21 |
Journal | Biomarkers in Medicine |
Volume | 8 |
Issue number | 7 |
DOIs | |
State | Published - 1 Aug 2014 |
Keywords
- Kawasaki disease
- biomarker
- cardiomyopathy
- cardiotoxicity
- congenital heart disease
- heart failure
- heart transplant
- natriuretic peptides
- postoperative
- pulmonary hypertension