Biological basis for statin therapy in stroke prevention

Research output: Contribution to journalReview articlepeer-review

29 Scopus citations


Hypercholesterolemia has not been considered an important risk factor for stroke; however, statin therapy reduces stroke in coronary heart disease patients. Statins may provide cerebrovascular protection through various mechanisms that include a reduction in the incidence of embolic stroke from cardiac, aortic and carotid sites, stabilization of vulnerable carotid atherosclerotic plaque, and improvement in cerebral blood flow. (C) 2000 Lippincott Williams and Wilkins.

Original languageEnglish
Pages (from-to)57-62
Number of pages6
JournalCurrent Opinion in Neurology
Issue number1
StatePublished - 2000
Externally publishedYes


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