Bioconductor: open software development for computational biology and bioinformatics.

Robert C. Gentleman, Vincent J. Carey, Douglas M. Bates, Ben Bolstad, Marcel Dettling, Sandrine Dudoit, Byron Ellis, Laurent Gautier, Yongchao Ge, Jeff Gentry, Kurt Hornik, Torsten Hothorn, Wolfgang Huber, Stefano Iacus, Rafael Irizarry, Friedrich Leisch, Cheng Li, Martin Maechler, Anthony J. Rossini, Gunther SawitzkiColin Smith, Gordon Smyth, Luke Tierney, Jean Y.H. Yang, Jianhua Zhang

Research output: Contribution to journalArticlepeer-review

9328 Scopus citations


The Bioconductor project is an initiative for the collaborative creation of extensible software for computational biology and bioinformatics. The goals of the project include: fostering collaborative development and widespread use of innovative software, reducing barriers to entry into interdisciplinary scientific research, and promoting the achievement of remote reproducibility of research results. We describe details of our aims and methods, identify current challenges, compare Bioconductor to other open bioinformatics projects, and provide working examples.

Original languageEnglish
Pages (from-to)R80
JournalGenome Biology
Issue number10
StatePublished - 2004
Externally publishedYes


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