TY - CHAP
T1 - Beyond supersecondary structure
T2 - The global properties of protein sequences
AU - Rackovsky, S.
PY - 2013
Y1 - 2013
N2 - Analysis of the global properties of protein sequences, rather than single-site or local properties, has been shown to lead to new understanding of folding and function. Here we describe the use of software which can describe sequences numerically in an orthonormal fashion, Fourier-analyze those sequences, and verify the statistical signi fi cance of the resulting Fourier coef fi cients. The resulting parameters can be used to study problems involving sequences from a unique perspective.
AB - Analysis of the global properties of protein sequences, rather than single-site or local properties, has been shown to lead to new understanding of folding and function. Here we describe the use of software which can describe sequences numerically in an orthonormal fashion, Fourier-analyze those sequences, and verify the statistical signi fi cance of the resulting Fourier coef fi cients. The resulting parameters can be used to study problems involving sequences from a unique perspective.
KW - Fourier analysis
KW - Global representation
KW - Sequence analysis
UR - http://www.scopus.com/inward/record.url?scp=84934436064&partnerID=8YFLogxK
U2 - 10.1007/978-1-62703-65-6_7
DO - 10.1007/978-1-62703-65-6_7
M3 - Chapter
C2 - 22987349
AN - SCOPUS:84934436064
SN - 9781627030649
T3 - Methods in Molecular Biology
SP - 107
EP - 114
BT - Protein Supersecondary Structures
PB - Humana Press Inc.
ER -