Benzoate-based room temperature ionic liquids - Thermal properties and glycosaminoglycan dissolution

Saravanababu Murugesan; John M. Wiencek; Rex X. Ren; Robert J. Linhardt

doi:10.1016/j.carbpol.2005.09.022

Benzoate-based room temperature ionic liquids - Thermal properties and glycosaminoglycan dissolution

Saravanababu Murugesan
, John M. Wiencek
, Rex X. Ren
, Robert J. Linhardt

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Abstract

Benzoate-based room temperature ionic liquids (RTILs) have been synthesized with cations of varying structures. The thermal properties of these RTILs have been characterized to understand their structure-property relationship. A subset of these benzoate-RTILs was found to be capable of dissolving highly charged polysaccharides, glycosaminoglycans (GAGs) to an extent of 10 mg/ml while PF₆ and BF₄ RTILs were not able to dissolve GAGs in significant quantities. The impact of the nature of the GAG counter-ion on GAG solubility is also addressed. The imidazolium salts of GAGs dissolved easier when compared to the sodium salts.

Original language	English
Pages (from-to)	268-271
Number of pages	4
Journal	Carbohydrate Polymers
Volume	63
Issue number	2
DOIs	https://doi.org/10.1016/j.carbpol.2005.09.022
State	Published - 3 Feb 2006
Externally published	Yes

Keywords

Glycosaminoglycans
RTILs

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10.1016/j.carbpol.2005.09.022

Cite this

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title = "Benzoate-based room temperature ionic liquids - Thermal properties and glycosaminoglycan dissolution",

abstract = "Benzoate-based room temperature ionic liquids (RTILs) have been synthesized with cations of varying structures. The thermal properties of these RTILs have been characterized to understand their structure-property relationship. A subset of these benzoate-RTILs was found to be capable of dissolving highly charged polysaccharides, glycosaminoglycans (GAGs) to an extent of 10 mg/ml while PF6 and BF4 RTILs were not able to dissolve GAGs in significant quantities. The impact of the nature of the GAG counter-ion on GAG solubility is also addressed. The imidazolium salts of GAGs dissolved easier when compared to the sodium salts.",

keywords = "Glycosaminoglycans, RTILs",

author = "Saravanababu Murugesan and Wiencek, \{John M.\} and Ren, \{Rex X.\} and Linhardt, \{Robert J.\}",

note = "Funding Information: We would like to thank NIH grant HL62244. We would also like to convey our thanks to Mr Kalpesh Parekh and Dr Lokesh Gakhar for their technical support with DSC. We would like to thank Professor Chang Ryu for giving us the access to TGA.",

year = "2006",

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doi = "10.1016/j.carbpol.2005.09.022",

language = "English",

volume = "63",

pages = "268--271",

journal = "Carbohydrate Polymers",

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T1 - Benzoate-based room temperature ionic liquids - Thermal properties and glycosaminoglycan dissolution

AU - Murugesan, Saravanababu

AU - Wiencek, John M.

AU - Ren, Rex X.

AU - Linhardt, Robert J.

N1 - Funding Information: We would like to thank NIH grant HL62244. We would also like to convey our thanks to Mr Kalpesh Parekh and Dr Lokesh Gakhar for their technical support with DSC. We would like to thank Professor Chang Ryu for giving us the access to TGA.

PY - 2006/2/3

Y1 - 2006/2/3

N2 - Benzoate-based room temperature ionic liquids (RTILs) have been synthesized with cations of varying structures. The thermal properties of these RTILs have been characterized to understand their structure-property relationship. A subset of these benzoate-RTILs was found to be capable of dissolving highly charged polysaccharides, glycosaminoglycans (GAGs) to an extent of 10 mg/ml while PF6 and BF4 RTILs were not able to dissolve GAGs in significant quantities. The impact of the nature of the GAG counter-ion on GAG solubility is also addressed. The imidazolium salts of GAGs dissolved easier when compared to the sodium salts.

AB - Benzoate-based room temperature ionic liquids (RTILs) have been synthesized with cations of varying structures. The thermal properties of these RTILs have been characterized to understand their structure-property relationship. A subset of these benzoate-RTILs was found to be capable of dissolving highly charged polysaccharides, glycosaminoglycans (GAGs) to an extent of 10 mg/ml while PF6 and BF4 RTILs were not able to dissolve GAGs in significant quantities. The impact of the nature of the GAG counter-ion on GAG solubility is also addressed. The imidazolium salts of GAGs dissolved easier when compared to the sodium salts.

KW - Glycosaminoglycans

KW - RTILs

UR - https://www.scopus.com/pages/publications/31344464214

U2 - 10.1016/j.carbpol.2005.09.022

DO - 10.1016/j.carbpol.2005.09.022

M3 - Article

AN - SCOPUS:31344464214

SN - 0144-8617

VL - 63

SP - 268

EP - 271

JO - Carbohydrate Polymers

JF - Carbohydrate Polymers

IS - 2

ER -

Benzoate-based room temperature ionic liquids - Thermal properties and glycosaminoglycan dissolution

Abstract

Keywords

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