Beating Heart Transplantation: How to Do It

Aravind Krishnan; Brandon A. Guenthart; Chawannuch Ruaengsri; Stefan Elde; Yuanjia Zhu; John Ward MacArthur; Y. Joseph Woo

doi:10.1177/15569845231220678

Beating Heart Transplantation: How to Do It

Aravind Krishnan, Brandon A. Guenthart, Chawannuch Ruaengsri, Stefan Elde, Yuanjia Zhu, John Ward MacArthur, Y. Joseph Woo

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Heart transplantation utilizing deceased after circulatory death (DCD) donors has expanded the donor pool through the use of ex vivo normothermic perfusion. Compared with brain death donation, the conventional method of performing DCD heart transplantation includes an additional period of warm and cold ischemia. We have developed a beating heart implantation technique that obliviates the need for a second cardioplegic arrest and the associated reperfusion injury. We hypothesize this reproducible method may improve short-term and long-term outcomes to mirror results seen in brain death donors and provide details on how to perform beating heart transplantation.

Original language	English
Pages (from-to)	88-91
Number of pages	4
Journal	Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
Volume	19
Issue number	1
DOIs	https://doi.org/10.1177/15569845231220678
State	Published - 1 Jan 2024
Externally published	Yes

Keywords

ex vivo organ perfusion
heart transplantation
organ preservation

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AU - Krishnan, Aravind

AU - Guenthart, Brandon A.

AU - Ruaengsri, Chawannuch

AU - Elde, Stefan

AU - Zhu, Yuanjia

AU - MacArthur, John Ward

AU - Woo, Y. Joseph

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AB - Heart transplantation utilizing deceased after circulatory death (DCD) donors has expanded the donor pool through the use of ex vivo normothermic perfusion. Compared with brain death donation, the conventional method of performing DCD heart transplantation includes an additional period of warm and cold ischemia. We have developed a beating heart implantation technique that obliviates the need for a second cardioplegic arrest and the associated reperfusion injury. We hypothesize this reproducible method may improve short-term and long-term outcomes to mirror results seen in brain death donors and provide details on how to perform beating heart transplantation.

KW - ex vivo organ perfusion

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KW - organ preservation

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Beating Heart Transplantation: How to Do It

Abstract

Keywords

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