Basic mechanisms of stroke prevention with lipid-lowering therapy

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4 Scopus citations


Cholesterol-lowering therapy has not been considered an important risk factor for stroke; however, lipid-lowering therapies reduce cerebrovascular events in patients with coronary heart disease (CHD). The basic mechanisms of cerebrovascular protection have emphasized reduced atheroemboli from the left ventricle and aortic arch, delayed carotid artery disease progression, stabilization of vulnerable carotid atherosclerotic plaque, and improvement in cerebral blood flow.

Original languageEnglish
Pages (from-to)120-125
Number of pages6
JournalCurrent Atherosclerosis Reports
Issue number2
StatePublished - Mar 2000
Externally publishedYes


  • Carotid Atherosclerosis
  • Cerebral Blood Flow
  • Pravastatin
  • Simvastatin
  • Stroke Prevention


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