Abstract
Extracts of B. subtilis contain somatostatin-like immunoactivity (1-20 pg per g wet weight cells). Two major forms were detected, one with reactivity in both N-and C- terminal immunoassays similar to somatostatin-28 and a second form reactive only in the C-terminal specific immunoassay similar to somatostatin-14. Both forms were active in a bioassay and the bioactivity was neutralized in the presence of antibody to the central, biologically active part of somatostatin-14. Preconditioned medium contained no detectable somatostatin whereas conditioned medium had 80-380 pg per liter.
Original language | English |
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Pages (from-to) | 713-719 |
Number of pages | 7 |
Journal | Biochemical and Biophysical Research Communications |
Volume | 127 |
Issue number | 3 |
DOIs | |
State | Published - 29 Mar 1985 |
Externally published | Yes |