Axillary Lymphadenectomy: A Prospective, Randomized Trial of 13 Factors Influencing Drainage, Including Early or Delayed Arm Mobilization

Jeanne A. Petrek, Margaret M. Peters, Subhadra Nori, Cynthia Knauer, David W. Kinne, Andre Rogatko

Research output: Contribution to journalArticlepeer-review

108 Scopus citations

Abstract

• Greater amount and duration of postoperative wound drainage after lymphadenectomy impede healing. We evaluated the influence of early vs delayed initiation of shoulder mobilization on postoperative drainage. Fifty-seven women with clinical stage I or II breast cancer were randomized to either early (postoperative day 2) or delayed (postoperative day 5) shoulder motion. Early vs delayed time of exercise initiation had no effect on total amount or duration of drainage, either as an inpatient or outpatient. The two groups were determined to be homogeneous as to age, breast size, weight, height, obesity, previous biopsy, excision of pectoralis minor, excision of thoracodorsal complex, level of axillary dissection, total number of lymph nodes, number of positive lymph nodes, lymphatic vessel invasion (with negative lymph nodes), and whether the dominant hand was on the side operated on. The two factors predicting greater drainage were large numbers of positive lymph nodes and no previous surgical biopsy (as in one-step procedure).

Original languageEnglish
Pages (from-to)378-382
Number of pages5
JournalArchives of Surgery
Volume125
Issue number3
DOIs
StatePublished - Mar 1990
Externally publishedYes

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