@article{01221b5e614d4ab29d62b4c036dd1d8e,
title = "Autoimmunity as the Consequence of a Spontaneous Mutation in Rasgrp1",
author = "Katrin Layer and Guosheng Lin and Alessio Nencion and Wei Hu and Adam Schmucker and Antov, \{Andrey N.\} and Xiaoyu Li and Satoshi Takamatsu and Timothy Chevassut and Dower, \{Nancy A.\} and Stang, \{Stacey L.\} and David Beier and Janet Buhlmann and Bronson, \{Roderick T.\} and Elkon, \{Keith B.\} and Stone, \{James C.\} and \{Van Parijs\}, Luk and Bing Lim",
note = "Funding Information: Katrin Layer Guosheng Lin Alessio Nencion Wei Hu Adam Schmucker Andrey N. Antov Xiaoyu Li Satoshi Takamatsu Timothy Chevassut Nancy A. Dower Stacey L. Stang David Beier Janet Buhlmann Roderick T. Bronson Keith B. Elkon James C. Stone Luk Van Parijs ∗
[email protected] Bing Lim ∗∗
[email protected] ∗ Corresponding author ∗∗ Corresponding author (Immunity 19 , 243–255; August 2003) The authors have agreed to retract the paper because of the falsification of the Western blot in Figure 6A. The figure shows a defect in Ras activation, labeled as RasGTP, following TCR engagement, in thymocytes isolated from a RasGRP1 lag mutant mouse strain. This data set is one of several that show signaling and functional deficiencies identified for cells with lost of function of RasGRP. The authors stand by the validity of the other figures, results, and interpretation in this paper. This matter was investigated by the Massachusetts Institute of Technology and the Office of Research Integrity at the United States Department of Health \& Human Services, which found that the figure was falsified by Luk Van Parijs, who is solely responsible. The authors deeply regret any inconvenience resulting from the publication of this data. ",
year = "2012",
month = may,
day = "25",
doi = "10.1016/j.immuni.2012.05.007",
language = "English",
volume = "36",
pages = "886",
journal = "Immunity",
issn = "1074-7613",
publisher = "Cell Press",
number = "5",
}