Autoimmune hepatitis in a patient with sickle cell disease

C. M. El Younis, A. D. Min, M. I. Fiel, F. M. Klion, S. N. Thung, B. Faire, C. M. Miller, H. C. Bodenheimer

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


In this report, we describe the case of a 28-yr-old woman with sickle cell anemia who presented with acute hepatic failure manifested by anorexia, malaise, painless jaundice, elevated aminotransferase activities, and severe coagulopathy. Liver biopsy revealed changes consistent with autoimmune hepatitis. Treatment with corticosteroids and azathioprine was followed by improvement in biochemical liver test results. The literature on sickle cell- associated liver diseases is reviewed.

Original languageEnglish
Pages (from-to)1016-1018
Number of pages3
JournalAmerican Journal of Gastroenterology
Issue number5
StatePublished - May 1996


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