Atypische antipsychotica

Translated title of the contribution: Atypical antipsychotics

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations


In recent years several new antipsychotics have come to market in the Netherlands (i.e. risperidone, olanzapine and quetiapine). These compounds are called atypical for their lack of the extrapyramidal side effects typical of older antipsychotics. Clozapine, which was developed earlier, is also an atypical antipsychotic drug. - The new antipsychotics have proven to be more effective than the old ones in reducing the negative symptoms and in improving the cognitive deficits of schizophrenia. Moreover, they indeed induce less extrapyramidal side effects than the older antipsychotics. - Head-to-head comparisons of the atypical antipsychotics are sparse. Studies comparing low-dose regimens of the typical antipsychotics with the atypical drugs as well as relapse prevention studies are needed before it can be decided whether the atypical drugs can replace the older compounds.

Translated title of the contributionAtypical antipsychotics
Original languageDutch
Pages (from-to)1627-1630
Number of pages4
JournalNederlands Tijdschrift voor Geneeskunde
Issue number34
StatePublished - 19 Aug 2000
Externally publishedYes


Dive into the research topics of 'Atypical antipsychotics'. Together they form a unique fingerprint.

Cite this