Atypical mole syndrome: Risk factor for cutaneous malignant melanoma and implications for management

Johnny Slade, Ashfaq A. Marghoob, Thomas G. Salopek, Darrell S. Rigel, Alfred W. Kopf, Robert S. Bart

Research output: Contribution to journalReview articlepeer-review

109 Scopus citations

Abstract

The incidence of malignant melanoma is increasing faster than that of any other cancer. It is important to identify subsets of the population at high risk of its development so that they can be observed more closely to identify early melanomas when they are curable. It has been reported worldwide that persons with the atypical mole (dysplastic nevus) syndrome are such a subset at increased risk. A risk gradient for the development of melanoma exists and varies from persons with one or two atypical moles and no family history of melanoma at one end of the spectrum to persons with the familial atypical multiple-mole melanoma syndrome at the other. Guidelines for the management of atypical mole syndrome are presented.

Original languageEnglish
Pages (from-to)479-494
Number of pages16
JournalJournal of the American Academy of Dermatology
Volume32
Issue number3
DOIs
StatePublished - Mar 1995
Externally publishedYes

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