Atypical Hemolytic-Uremic Syndrome Following Obstetric Hemorrhage in the Setting of Fetal Demise and Placenta Accreta: A Case Report

Ryan Wang, Chloe Getrajdman, Daniel Blech, Sarp Aksel, Samuel Bender, Daniel Katz

Research output: Contribution to journalArticlepeer-review

Abstract

Multiple disease processes can contribute to coagulopathy in the setting of intrauterine fetal demise. A 34-year-old woman with multiple prior uterine surgeries presented for dilation and evacuation of a fetal demise at 17 weeks. Her case was complicated by significant hemorrhage and coagulopathy requiring massive transfusion and hysterectomy. She developed atypical hemolytic-uremic syndrome postoperatively. Pathology identified a focal placenta accreta. While not known to present together, fetal demise, placenta accreta, and atypical hemolytic-uremic syndrome can occur in the same patient with an overlapping presentation. Early hematology consultation is recommended in the setting of ongoing hemolysis and renal dysfunction.

Original languageEnglish
Pages (from-to)e01476
JournalA&A practice
Volume15
Issue number5
DOIs
StatePublished - 14 May 2021

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