Atypical endovascular cells in SARS-CoV-2 pneumonia

Nicholas Barna, Jennifer Chapman, Kenneth Hutchins, Fintan Garavan

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

The autopsy findings for 3 cases of SARS-(CoV-2) pneumonia-related deaths are reported with pulmonary histology and immunohistochemistry findings. In 2 cases (cases 1 and 2), the time interval from presentation to death was approximately 1 week, whereas for case 3, the time interval from presentation to death was hours. Case 1 and case 2 presented with shortness of breath, cough, and flu-like symptoms. The decedent from case 3 died shortly after presenting to a local emergency room with high fever, chest and abdominal pain, and shortness of breath. All 3 cases had 1 or more comorbidities. The postmortem interval for cases 1 and 2 was 2 weeks as they died at sea and were stored on board within the respective cruise ships' refrigeration units, whereas case 3 was examined within 24 hours of death. The autopsies were conducted at the Miami-Dade County Medical Examiners Department under routine infectious precautions. Salient clinical history and autopsy findings are summarized. Microscopic examination revealed pneumonia with associated atypical endovascular cells.

Original languageEnglish
Pages (from-to)E61-E63
JournalAmerican Journal of Forensic Medicine and Pathology
Volume41
Issue number4
DOIs
StatePublished - Dec 2020
Externally publishedYes

Keywords

  • Autopsy
  • Immunohistochemistry
  • SARS-(CoV-2) pneumonia

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