Atrial Fibrillation and Diabetes Mellitus: JACC Review Topic of the Week

A. Wang, Jennifer B. Green, Jonathan L. Halperin, Jonathan P. Piccini

Research output: Contribution to journalReview articlepeer-review

186 Scopus citations


Diabetes mellitus is one of the most common chronic medical conditions, and is a risk factor for the development of atrial fibrillation (AF). The presence of diabetes in patients with AF is associated with increased symptom burden and increased cardiovascular and cerebrovascular mortality. The pathophysiology of diabetes-related AF is not fully understood, but is related to structural, electrical, electromechanical, and autonomic remodeling. This paper reviews the complex interaction between diabetes and AF, and explores its effect on the prevention and treatment of AF.

Original languageEnglish
Pages (from-to)1107-1115
Number of pages9
JournalJournal of the American College of Cardiology
Issue number8
StatePublished - 27 Aug 2019


  • atrial fibrillation
  • diabetes mellitus


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