TY - JOUR
T1 - Atopic Dermatitis
T2 - Systemic Immunosuppressive Therapy
AU - Akhavan, Arash
AU - Rudikoff, Donald
PY - 2008/6
Y1 - 2008/6
N2 - Atopic dermatitis (AD) is a pruritic, relapsing skin disorder that negatively impacts the quality of life of those affected and that of their families. Treatment options for AD encompass a variety of emollients, topical corticosteroids, topical immunomodulators, phototherapy, and systemic agents. Such agents as systemic corticosteroids, cyclosporine, azathioprine, interferon-γ, methotrexate, and mycophenolate mofetil have been shown to be efficacious in the treatment of moderate-to-severe AD but are not officially approved for this purpose. In this article, we review some of the data supporting efficacy of these medications and discuss some of the adverse events associated with their use.
AB - Atopic dermatitis (AD) is a pruritic, relapsing skin disorder that negatively impacts the quality of life of those affected and that of their families. Treatment options for AD encompass a variety of emollients, topical corticosteroids, topical immunomodulators, phototherapy, and systemic agents. Such agents as systemic corticosteroids, cyclosporine, azathioprine, interferon-γ, methotrexate, and mycophenolate mofetil have been shown to be efficacious in the treatment of moderate-to-severe AD but are not officially approved for this purpose. In this article, we review some of the data supporting efficacy of these medications and discuss some of the adverse events associated with their use.
UR - http://www.scopus.com/inward/record.url?scp=46649117668&partnerID=8YFLogxK
U2 - 10.1016/j.sder.2008.04.004
DO - 10.1016/j.sder.2008.04.004
M3 - Article
C2 - 18620137
AN - SCOPUS:46649117668
SN - 1085-5629
VL - 27
SP - 151
EP - 155
JO - Seminars in Cutaneous Medicine and Surgery
JF - Seminars in Cutaneous Medicine and Surgery
IS - 2
ER -