At the Crossroads between Cell Polarity and Adhesion in Neocortical Development

Sergei Y. Sokol

doi:10.1016/j.devcel.2017.05.017

At the Crossroads between Cell Polarity and Adhesion in Neocortical Development

Research output: Contribution to journal › Short survey › peer-review

Abstract

In this issue of Developmental Cell, Jossin et al. (2017) show that the tumor suppressor protein Lgl1 interacts with N-cadherin to stabilize apical junctions in brain stem cells. Neural progenitors lacking Lgl1 had decreased N-cadherin internalization and abnormal cell junctions, generating an ectopic neuronal layer that resembles cerebral cortex abnormalities in humans.

Original language	English
Pages (from-to)	453-454
Number of pages	2
Journal	Developmental Cell
Volume	41
Issue number	5
DOIs	https://doi.org/10.1016/j.devcel.2017.05.017
State	Published - 5 Jun 2017

Access to Document

10.1016/j.devcel.2017.05.017

Cite this

@article{d611d0a9984745a3839234af47ea14d8,

title = "At the Crossroads between Cell Polarity and Adhesion in Neocortical Development",

abstract = "In this issue of Developmental Cell, Jossin et al. (2017) show that the tumor suppressor protein Lgl1 interacts with N-cadherin to stabilize apical junctions in brain stem cells. Neural progenitors lacking Lgl1 had decreased N-cadherin internalization and abnormal cell junctions, generating an ectopic neuronal layer that resembles cerebral cortex abnormalities in humans.",

author = "Sokol, {Sergei Y.}",

note = "Publisher Copyright: {\textcopyright} 2017",

year = "2017",

month = jun,

day = "5",

doi = "10.1016/j.devcel.2017.05.017",

language = "English",

volume = "41",

pages = "453--454",

journal = "Developmental Cell",

issn = "1534-5807",

publisher = "Cell Press",

number = "5",

}

TY - JOUR

T1 - At the Crossroads between Cell Polarity and Adhesion in Neocortical Development

AU - Sokol, Sergei Y.

PY - 2017/6/5

Y1 - 2017/6/5

N2 - In this issue of Developmental Cell, Jossin et al. (2017) show that the tumor suppressor protein Lgl1 interacts with N-cadherin to stabilize apical junctions in brain stem cells. Neural progenitors lacking Lgl1 had decreased N-cadherin internalization and abnormal cell junctions, generating an ectopic neuronal layer that resembles cerebral cortex abnormalities in humans.

AB - In this issue of Developmental Cell, Jossin et al. (2017) show that the tumor suppressor protein Lgl1 interacts with N-cadherin to stabilize apical junctions in brain stem cells. Neural progenitors lacking Lgl1 had decreased N-cadherin internalization and abnormal cell junctions, generating an ectopic neuronal layer that resembles cerebral cortex abnormalities in humans.

UR - http://www.scopus.com/inward/record.url?scp=85020216892&partnerID=8YFLogxK

U2 - 10.1016/j.devcel.2017.05.017

DO - 10.1016/j.devcel.2017.05.017

M3 - Short survey

C2 - 28586640

AN - SCOPUS:85020216892

SN - 1534-5807

VL - 41

SP - 453

EP - 454

JO - Developmental Cell

JF - Developmental Cell

IS - 5

ER -

At the Crossroads between Cell Polarity and Adhesion in Neocortical Development

Abstract

Access to Document

Fingerprint

Cite this