Asymptomatic circulation of HEV71 in Norway

Elisabet Witsø, Gustavo Palacios, Kjersti S. Rønningen, Ondrej Cinek, Diana Janowitz, Marian Rewers, Bjørn Grinde, W. Ian Lipkin

Research output: Contribution to journalArticlepeer-review

61 Scopus citations

Abstract

Widespread circulation of human enterovirus 71 was discovered in a prospective study of fecal samples obtained from healthy Norwegian children. Molecular characterization of the virus determined that it belonged to genotype C1. Complete sequencing of this strain, HEV71 804/NO/03, revealed differences in the 5′UTR and polymerase with respect to more pathogenic genotypes that may explain its reduced neurovirulence.

Original languageEnglish
Pages (from-to)19-29
Number of pages11
JournalVirus Research
Volume123
Issue number1
DOIs
StatePublished - Jan 2007
Externally publishedYes

Keywords

  • Enterovirus 71
  • Epidemiology
  • Molecular typing

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