Association of T cell acute lymphoblastic leukemia and histiocytic medullary reticulosis

Fred Rosner, Hans W. Grünwald

Research output: Contribution to journalReview articlepeer-review

12 Scopus citations

Abstract

Seventeen reported cases of acute lymphoblastic leukemia that terminated in a clinical picture of histiocytic medullary reticulosis were reviewed. Using the presence of T cell markers, mediastinal mass, or very high initial white blood cell count as suggestive of T cell acute lymphoblastic leukemia, nine of 13 evaluable cases fulfilled such criteria. This review raises the possibility that the histiocytic medullary reticulosis appearing in the course of T cell acute lymphoblastic leukemia is the result of lymphokine production by the leukemic cells.

Original languageEnglish
Pages (from-to)910-914
Number of pages5
JournalAmerican Journal of Medicine
Volume77
Issue number5
DOIs
StatePublished - Nov 1984

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