Association of Blastocystis hominis with signs and symptoms of human disease

D. J. Sheehan, B. G. Raucher, J. C. McKitrick

Research output: Contribution to journalArticlepeer-review

133 Scopus citations


Purged stools from 389 patients were evaluated microscopically for the presence of Blastocystis hominis. A total of five or more Blastocystis hominis cells per 40x field were observed in 43 patients (11%), and Blastocystis hominis was the only intestinal parasite present in 23 (6%) of those patients. Of the 23 patients, 19 had symptoms which included abdominal discomfort (15 patients), anorexia (10 patients), diarrhea (9 patients), and flatus (9 patients). The remaining four patients were asymptomatic. The proportion of eosinophils in the peripheral blood ranged from 4 to 12% in 11 (58%) of the symptomatic patients. Absolute eosinophil counts were greater than 250/μl in 8 patients and greater than 400/μl in 5 patients. Eosinophilia was not observed in the remaining symptomatic or asymptomatic patients. This study supports the emerging concept of the role of Blastocystis hominis as an intestinal parasite causative of human disease.

Original languageEnglish
Pages (from-to)548-550
Number of pages3
JournalJournal of Clinical Microbiology
Issue number4
StatePublished - 1986
Externally publishedYes


Dive into the research topics of 'Association of Blastocystis hominis with signs and symptoms of human disease'. Together they form a unique fingerprint.

Cite this