The association of refractory anemia with partial deletion of the long arm of one No. 5 chromosome (5q−) has been reported in six patients within the last two years. We wish to report an additional patient with refractory anemia and an acquired chromosomal deletion, del(5)(q15), in a direct bone‐marrow preparation. The specificity of this deletion for refractory anemia is discussed. It remains to be seen whether patients with refractory anemia and 5q− tend to develop acute leukemia, as has been recently suggested.

Original languageEnglish
Pages (from-to)269-272
Number of pages4
JournalAmerican Journal of Hematology
Issue number3
StatePublished - 1978


  • 5q deletion
  • acute leukemia
  • chromosomal deletion
  • refractory anemia


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