TY - JOUR
T1 - Association between estrogen receptors and weight in women with breast cancer
AU - Papatestas, Angelos E.
AU - Panveliwalla, Daraius
AU - Pertsemlidis, Demetrius
AU - Mulvihill, Michael
AU - Aufses, Arthur H.
PY - 1980/2
Y1 - 1980/2
N2 - A significant association between body weight and estrogen receptor protein (ERP) was noted in 83 women with primary and metastatic breast cancer. Thirteen of 34 (54%) women with weight >150 lb had low or absent receptor protein (<10 femtomoles/mg of cytoplasmic protein) compared to 15 of 59 (25%) women with weight <150 lb (P <0.025). The observed association was stronger in the group of 62 postmenopausal women (P <0.01). The findings suggest that the endocrine and metabolic milieu in women with increased weight favors autonomous growth of breast cancer, and adjuvant treatment in this group should be planned accordingly.
AB - A significant association between body weight and estrogen receptor protein (ERP) was noted in 83 women with primary and metastatic breast cancer. Thirteen of 34 (54%) women with weight >150 lb had low or absent receptor protein (<10 femtomoles/mg of cytoplasmic protein) compared to 15 of 59 (25%) women with weight <150 lb (P <0.025). The observed association was stronger in the group of 62 postmenopausal women (P <0.01). The findings suggest that the endocrine and metabolic milieu in women with increased weight favors autonomous growth of breast cancer, and adjuvant treatment in this group should be planned accordingly.
KW - breast cancer
KW - estrogen receptors
KW - weight
UR - http://www.scopus.com/inward/record.url?scp=0018899412&partnerID=8YFLogxK
U2 - 10.1002/jso.2930130213
DO - 10.1002/jso.2930130213
M3 - Article
C2 - 7359923
AN - SCOPUS:0018899412
SN - 0022-4790
VL - 13
SP - 177
EP - 180
JO - Journal of Surgical Oncology
JF - Journal of Surgical Oncology
IS - 2
ER -