Association between epicardial fat volume and fractional flow reserve: An analysis of the determination of fractional flow reserve (DeFACTO) study

Ashley Beecy, Bríain Hartaigh, Joshua Schulman-Marcus, Khalil Anchouche, Heidi Gransar, Subhi Al'Aref, Kimberly Elmore, Fay Y. Lin, James K. Min, Jessica M. Peña

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Background: This study examines the relationship between epicardial fat volume (EFV) and lesion-specific ischemia by fractional flow reserve (FFR). Methods: In a study of 173 patients (63.0 ± 8.3 years) undergoing FFR, EFV was determined using cardiac computed tomography. Relationships between EFV and FFR were assessed using multivariable linear and logistic regression. Results: Using multivariable linear and logistic regression, no association between EFV and FFR was observed (β [SE] = −0.001 [0.003], P = 0.6, OR [95% CI]: 1.02 [0.94–1.11], P = 0.64, respectively). Conclusion: In patients with suspected or known coronary artery disease undergoing invasive angiography, EFV was not associated with FFR.

Original languageEnglish
Pages (from-to)30-34
Number of pages5
JournalClinical Imaging
Volume51
DOIs
StatePublished - Sep 2018
Externally publishedYes

Keywords

  • Coronary artery disease
  • Epicardial adipose tissue
  • Epicardial fat volume
  • Fractional flow reserve

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