Assessment of ventricular function in arterial hypertension with radionuclide ventriculography

Maria Radice, Alberto Albertini, Claudio Alli, Cristina Canciani, Marco Di Tullio, Marcella Manzini, Giancarlo Mariotti, Elena Salmoirago, Emanuela Taioli, Giorgio Zatta, Gian Luigi Tarolo

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5 Scopus citations


Diastolic function of the left ventricle was assessed in 29 untreated patients with mild to moderate hypertension and in 21 normotensive control subjects using gated radionuclide ventriculography. In hypertensive patients, the time to peak filling rate was significantly longer (p <0.01) than that in control subjects, and first-third filling fraction and peak filling rate were significantly reduced (p <0.001). The ejection fraction and peak ejection rate were also significantly reduced in hypertensive patients (p <0.001). No relation was observed between diastolic functional impairment and age, cardiac hypertrophy, or severity of hypertension. Thus, early impairment of ventricular filling is present in hypertension, even in young patients without evidence of cardiac hypertrophy.

Original languageEnglish
Pages (from-to)133-135
Number of pages3
JournalAmerican Journal of Medicine
Issue number3 SUPPL. 1
StatePublished - 11 Mar 1988
Externally publishedYes


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