Assessment of the neurogenic flare reaction in small-fiber neuropathies

A. Bickel; H. H. Krämer; M. J. Hilz; F. Birklein; B. Neundörfer; M. Schmelz

doi:10.1212/WNL.59.6.917

Assessment of the neurogenic flare reaction in small-fiber neuropathies

A. Bickel, H. H. Krämer, M. J. Hilz, F. Birklein, B. Neundörfer, M. Schmelz

Research output: Contribution to journal › Article › peer-review

60 Scopus citations

Abstract

To improve sensitivity of the analysis of axon reflex flare reaction, the authors used a laser Doppler scanner and analyzed flare intensity and size induced by histamine iontophoresis simultaneously at the foot and thigh in patients with small-fiber neuropathy (n = 10) and controls (n = 9). Flare size, but not laser Doppler flux, clearly distinguished patients from controls at both locations (p < 0.01) and may be useful for evaluation of small-fiber neuropathies.

Original language	English
Pages (from-to)	917-919
Number of pages	3
Journal	Neurology
Volume	59
Issue number	6
DOIs	https://doi.org/10.1212/WNL.59.6.917
State	Published - 24 Sep 2002
Externally published	Yes

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AU - Neundörfer, B.

AU - Schmelz, M.

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AB - To improve sensitivity of the analysis of axon reflex flare reaction, the authors used a laser Doppler scanner and analyzed flare intensity and size induced by histamine iontophoresis simultaneously at the foot and thigh in patients with small-fiber neuropathy (n = 10) and controls (n = 9). Flare size, but not laser Doppler flux, clearly distinguished patients from controls at both locations (p < 0.01) and may be useful for evaluation of small-fiber neuropathies.

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Assessment of the neurogenic flare reaction in small-fiber neuropathies

Abstract

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