Assessment of reproductive disorders and birth defects in communities near hazardous chemical sites. II. Female reproductive disorders

Anthony R. Scialli; Shanna H. Swan; Robert W. Amler; Donna D. Baird; Brenda Eskenazi; Ginger Gist; Maureen C. Hatch; James S. Kesner; Grace K. Lemasters; Michele Marcus; Maureen E. Paul; Paul Schulte; Zachary Taylor; Allen J. Wilcox; Chris Zahniser

doi:10.1016/S0890-6238(96)00107-4

Assessment of reproductive disorders and birth defects in communities near hazardous chemical sites. II. Female reproductive disorders

Anthony R. Scialli, Shanna H. Swan, Robert W. Amler, Donna D. Baird, Brenda Eskenazi, Ginger Gist, Maureen C. Hatch, James S. Kesner, Grace K. Lemasters, Michele Marcus, Maureen E. Paul, Paul Schulte, Zachary Taylor, Allen J. Wilcox, Chris Zahniser

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Members of the workgroup on female reproductive disorders discussed methods to evaluate five principal functions: menstrual dysfunction, infertility, pregnancy loss, lactation disorders, and pregnancy complications. To test each function, a nested strategy was considered, based on progressive levels of effort available to conduct field investigations. This strategy was analogous to the three-tier classification of biomarkers used by other workshops. The lowest level of effort, corresponding to Tier 1, consists only of questionnaires, diaries, and reviews of maternal and infant medical records. The medium level of effort (Tier 2) collects data from questionnaires and diaries, and some biologic specimens. Suggested laboratory analyses included measurement of progesterone in saliva and several glycoprotein hormones in urine that evaluate menstrual dysfunction, infertility, and pregnancy loss. The highest level of effort (Tier 3) involves prospective collection of diary information and simultaneous collection of biological specimens.

Original language	English
Pages (from-to)	231-242
Number of pages	12
Journal	Reproductive Toxicology
Volume	11
Issue number	2-3
DOIs	https://doi.org/10.1016/S0890-6238(96)00107-4
State	Published - 1997
Externally published	Yes

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Scialli, A. R., Swan, S. H., Amler, R. W., Baird, D. D., Eskenazi, B., Gist, G., Hatch, M. C., Kesner, J. S., Lemasters, G. K., Marcus, M., Paul, M. E., Schulte, P., Taylor, Z., Wilcox, A. J., & Zahniser, C. (1997). Assessment of reproductive disorders and birth defects in communities near hazardous chemical sites. II. Female reproductive disorders. Reproductive Toxicology, 11(2-3), 231-242. https://doi.org/10.1016/S0890-6238(96)00107-4

@article{02cc5052e46d4df2a74a0eb35f9445b1,

title = "Assessment of reproductive disorders and birth defects in communities near hazardous chemical sites. II. Female reproductive disorders",

abstract = "Members of the workgroup on female reproductive disorders discussed methods to evaluate five principal functions: menstrual dysfunction, infertility, pregnancy loss, lactation disorders, and pregnancy complications. To test each function, a nested strategy was considered, based on progressive levels of effort available to conduct field investigations. This strategy was analogous to the three-tier classification of biomarkers used by other workshops. The lowest level of effort, corresponding to Tier 1, consists only of questionnaires, diaries, and reviews of maternal and infant medical records. The medium level of effort (Tier 2) collects data from questionnaires and diaries, and some biologic specimens. Suggested laboratory analyses included measurement of progesterone in saliva and several glycoprotein hormones in urine that evaluate menstrual dysfunction, infertility, and pregnancy loss. The highest level of effort (Tier 3) involves prospective collection of diary information and simultaneous collection of biological specimens.",

author = "Scialli, {Anthony R.} and Swan, {Shanna H.} and Amler, {Robert W.} and Baird, {Donna D.} and Brenda Eskenazi and Ginger Gist and Hatch, {Maureen C.} and Kesner, {James S.} and Lemasters, {Grace K.} and Michele Marcus and Paul, {Maureen E.} and Paul Schulte and Zachary Taylor and Wilcox, {Allen J.} and Chris Zahniser",

note = "Funding Information: Acknowledgmen-tT his publication was supportedp artially by funds from the ComprehensiveE nvironmentalR esponse,C ompensation,a nd Liability Act trust fund through the Agency for Toxic Substancesa nd Disease Registry, Public Health Service, U.S. Departmento f Health and Human Services.",

year = "1997",

doi = "10.1016/S0890-6238(96)00107-4",

language = "English",

volume = "11",

pages = "231--242",

journal = "Reproductive Toxicology",

issn = "0890-6238",

publisher = "Elsevier Inc.",

number = "2-3",

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Scialli, AR, Swan, SH, Amler, RW, Baird, DD, Eskenazi, B, Gist, G, Hatch, MC, Kesner, JS, Lemasters, GK, Marcus, M, Paul, ME, Schulte, P, Taylor, Z, Wilcox, AJ & Zahniser, C 1997, 'Assessment of reproductive disorders and birth defects in communities near hazardous chemical sites. II. Female reproductive disorders', Reproductive Toxicology, vol. 11, no. 2-3, pp. 231-242. https://doi.org/10.1016/S0890-6238(96)00107-4

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AU - Scialli, Anthony R.

AU - Swan, Shanna H.

AU - Amler, Robert W.

AU - Baird, Donna D.

AU - Eskenazi, Brenda

AU - Gist, Ginger

AU - Hatch, Maureen C.

AU - Kesner, James S.

AU - Lemasters, Grace K.

AU - Marcus, Michele

AU - Paul, Maureen E.

AU - Schulte, Paul

AU - Taylor, Zachary

AU - Wilcox, Allen J.

AU - Zahniser, Chris

N1 - Funding Information: Acknowledgmen-tT his publication was supportedp artially by funds from the ComprehensiveE nvironmentalR esponse,C ompensation,a nd Liability Act trust fund through the Agency for Toxic Substancesa nd Disease Registry, Public Health Service, U.S. Departmento f Health and Human Services.

PY - 1997

Y1 - 1997

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Assessment of reproductive disorders and birth defects in communities near hazardous chemical sites. II. Female reproductive disorders

Abstract

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