TY - JOUR
T1 - Assessment of myocardial recovery in a patient with acute myocarditis supported with a left ventricular assist device
T2 - A case report
AU - Maybaum, Simon
AU - Stockwell, Philip
AU - Naka, Yoshi
AU - Catanese, Katherine
AU - Flannery, Margaret
AU - Fisher, Peter
AU - Oz, Mehmet
AU - Mancini, Donna
N1 - Funding Information:
Supported by the Einthoven Fund, New York, New York.
PY - 2003/2/1
Y1 - 2003/2/1
N2 - Acute myocarditis may present with profound hemodynamic compromise; however, spontaneous resolution of the inflammatory process may occur in up to half of such patients. In patients with fulminant myocarditis, mechanical circulatory support may serve as a bridge to myocardial recovery. In this report we describe a 35-year-old man with acute myocarditis who required left ventricular assist device support as a bridge to recovery, and suggest a method for determining the suitability and timing of device explantation. A combination of echocardiography, right heart catheterization, exercise testing and serial endomyocardial biopsies was used to determine the resolution of myocarditis, recovery of myocardial function and timing for device explantation. Successful device explantation was performed after 37 days of device support. Further study is required to assess the role of ventricular assist devices in combination with immunosuppressive therapy in the management of fulminant myocarditis.
AB - Acute myocarditis may present with profound hemodynamic compromise; however, spontaneous resolution of the inflammatory process may occur in up to half of such patients. In patients with fulminant myocarditis, mechanical circulatory support may serve as a bridge to myocardial recovery. In this report we describe a 35-year-old man with acute myocarditis who required left ventricular assist device support as a bridge to recovery, and suggest a method for determining the suitability and timing of device explantation. A combination of echocardiography, right heart catheterization, exercise testing and serial endomyocardial biopsies was used to determine the resolution of myocarditis, recovery of myocardial function and timing for device explantation. Successful device explantation was performed after 37 days of device support. Further study is required to assess the role of ventricular assist devices in combination with immunosuppressive therapy in the management of fulminant myocarditis.
UR - https://www.scopus.com/pages/publications/0037314334
U2 - 10.1016/S1053-2498(02)00488-6
DO - 10.1016/S1053-2498(02)00488-6
M3 - Article
C2 - 12581771
AN - SCOPUS:0037314334
SN - 1053-2498
VL - 22
SP - 202
EP - 209
JO - Journal of Heart and Lung Transplantation
JF - Journal of Heart and Lung Transplantation
IS - 2
ER -