TY - JOUR
T1 - Assessment of central corneal thickness using optical coherence tomography
AU - Fishman, Gary R.
AU - Pons, Mauricio E.
AU - Seedor, John A.
AU - Liebmann, Jeffrey M.
AU - Ritch, Robert
N1 - Funding Information:
Supported in part by the William Endico Research Fund of the New York Glaucoma Research Institute, New York, New York, USA.
PY - 2005/4
Y1 - 2005/4
N2 - Purpose: To demonstrate the capability of model OCT3 optical coherence tomographer to evaluate central corneal thickness (CCT) in normal human corneas in vivo and compare the results with the those of standard ultrasound (US) pachymetry and Orbscan. Setting: New York Eye & Ear Infirmary Resident Clinic, New York, New York, USA. Methods: The CCT in 22 eyes of 11 subjects was determined with the OCT3 (Carl Zeiss Meditec), Orbscan (Bausch & Lomb, Inc.), and US pachymetry (DGH Technology, Inc.). Three central corneal scans of each eye were obtained using the OCT3. First, OCT3 data were processed using the standard OCT software program (OCT3std). Second, OCT3 raw data were exported and measurements were repeated using Scion Image for Windows program (OCT3sci). The OCT3 and Orbscan results were compared with the mean of 5 US pachymetry measurements in each eye. Results: The OCT3std, OCT3sci, and Orbscan CCT measurements showed high correlations with US pachymetry (r = 0.981, r = 0.984, and r = 0.942, respectively; P<.0001). Bland-Altman analysis showed a high level of agreement between US pachymetry and OCT3 techniques but not Orbscan. High repeatability for OCT3std (r2 = 0.05) and OCT3sci (r2 = 0.01) was also seen. Conclusion: Results show the OCT3 is an accurate, noninvasive, and reproducible technique for evaluation of CCT.
AB - Purpose: To demonstrate the capability of model OCT3 optical coherence tomographer to evaluate central corneal thickness (CCT) in normal human corneas in vivo and compare the results with the those of standard ultrasound (US) pachymetry and Orbscan. Setting: New York Eye & Ear Infirmary Resident Clinic, New York, New York, USA. Methods: The CCT in 22 eyes of 11 subjects was determined with the OCT3 (Carl Zeiss Meditec), Orbscan (Bausch & Lomb, Inc.), and US pachymetry (DGH Technology, Inc.). Three central corneal scans of each eye were obtained using the OCT3. First, OCT3 data were processed using the standard OCT software program (OCT3std). Second, OCT3 raw data were exported and measurements were repeated using Scion Image for Windows program (OCT3sci). The OCT3 and Orbscan results were compared with the mean of 5 US pachymetry measurements in each eye. Results: The OCT3std, OCT3sci, and Orbscan CCT measurements showed high correlations with US pachymetry (r = 0.981, r = 0.984, and r = 0.942, respectively; P<.0001). Bland-Altman analysis showed a high level of agreement between US pachymetry and OCT3 techniques but not Orbscan. High repeatability for OCT3std (r2 = 0.05) and OCT3sci (r2 = 0.01) was also seen. Conclusion: Results show the OCT3 is an accurate, noninvasive, and reproducible technique for evaluation of CCT.
UR - http://www.scopus.com/inward/record.url?scp=19344369632&partnerID=8YFLogxK
U2 - 10.1016/j.jcrs.2004.09.021
DO - 10.1016/j.jcrs.2004.09.021
M3 - Article
C2 - 15899446
AN - SCOPUS:19344369632
SN - 0886-3350
VL - 31
SP - 707
EP - 711
JO - Journal of Cataract and Refractive Surgery
JF - Journal of Cataract and Refractive Surgery
IS - 4
ER -