Artificial Intelligence and Machine Learning in Perioperative Acute Kidney Injury

Kullaya Takkavatakarn, Ira S. Hofer

Research output: Contribution to journalReview articlepeer-review


Acute kidney injury (AKI) is a common complication after a surgery, especially in cardiac and aortic procedures, and has a significant impact on morbidity and mortality. Early identification of high-risk patients and providing effective prevention and therapeutic approach are the main strategies for reducing the possibility of perioperative AKI. Consequently, several risk-prediction models and risk assessment scores have been developed for the prediction of perioperative AKI. However, a majority of these risk scores are only derived from preoperative data while the intraoperative time-series monitoring data such as heart rate and blood pressure were not included. Moreover, the complexity of the pathophysiology of AKI, as well as its nonlinear and heterogeneous nature, imposes limitations on the use of linear statistical techniques. The development of clinical medicine's digitization, the widespread availability of electronic medical records, and the increase in the use of continuous monitoring have generated vast quantities of data. Machine learning has recently shown promise as a method for automatically integrating large amounts of data in predicting the risk of perioperative outcomes. In this article, we discussed the development, limitations of existing work, and the potential future direction of models using machine learning techniques to predict AKI after a surgery.

Original languageEnglish
Pages (from-to)53-60
Number of pages8
JournalAdvances in Kidney Disease and Health
Issue number1
StatePublished - Jan 2023


  • Acute kidney injury
  • Artificial intelligence
  • Machine learning
  • Perioperative
  • Prediction model


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