Arterial Wall function is associated with cognitive performance primarily in elderly with type 2 diabetes

Ramit Ravona-Springer; Salo Haratz; David Tanne; James Schmeidler; Shai Efrati; Clive Rosendorff; Michal Schnaider Beeri; Jeremy M. Silverman

doi:10.3233/JAD-141197

Arterial Wall function is associated with cognitive performance primarily in elderly with type 2 diabetes

Ramit Ravona-Springer, Salo Haratz, David Tanne, James Schmeidler, Shai Efrati, Clive Rosendorff, Michal Schnaider Beeri, Jeremy M. Silverman

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Regression analyses compared 41 type 2 diabetes (T2D) and 131 non-T2D cognitively normal elderly males on the associations of arterial wall function measures [large artery elasticity index (LAEI), small artery elasticity index (SAEI), systemic vascular resistance (SVR), and total vascular impedance (TVI)] with cognitive performance (memory, language, and executive functions), controlling for socio-demographic and cardiovascular factors. Higher LAEI and lower TVI were significantly associated with better executive functions performance in T2D but not in non-T2D subjects. Lower TVI was more associated with better language performance in T2D. Results suggest that arterial wall function is associated with cognition in T2D.

Original language	English
Pages (from-to)	687-693
Number of pages	7
Journal	Journal of Alzheimer's Disease
Volume	44
Issue number	2
DOIs	https://doi.org/10.3233/JAD-141197
State	Published - 2015

Keywords

Arterial wall function
cognitive function
large artery elasticity index
total vascular impedance
type 2 diabetes

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10.3233/JAD-141197

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abstract = "Regression analyses compared 41 type 2 diabetes (T2D) and 131 non-T2D cognitively normal elderly males on the associations of arterial wall function measures [large artery elasticity index (LAEI), small artery elasticity index (SAEI), systemic vascular resistance (SVR), and total vascular impedance (TVI)] with cognitive performance (memory, language, and executive functions), controlling for socio-demographic and cardiovascular factors. Higher LAEI and lower TVI were significantly associated with better executive functions performance in T2D but not in non-T2D subjects. Lower TVI was more associated with better language performance in T2D. Results suggest that arterial wall function is associated with cognition in T2D.",

keywords = "Arterial wall function, cognitive function, large artery elasticity index, total vascular impedance, type 2 diabetes",

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AU - Ravona-Springer, Ramit

AU - Haratz, Salo

AU - Tanne, David

AU - Schmeidler, James

AU - Efrati, Shai

AU - Rosendorff, Clive

AU - Beeri, Michal Schnaider

AU - Silverman, Jeremy M.

PY - 2015

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AB - Regression analyses compared 41 type 2 diabetes (T2D) and 131 non-T2D cognitively normal elderly males on the associations of arterial wall function measures [large artery elasticity index (LAEI), small artery elasticity index (SAEI), systemic vascular resistance (SVR), and total vascular impedance (TVI)] with cognitive performance (memory, language, and executive functions), controlling for socio-demographic and cardiovascular factors. Higher LAEI and lower TVI were significantly associated with better executive functions performance in T2D but not in non-T2D subjects. Lower TVI was more associated with better language performance in T2D. Results suggest that arterial wall function is associated with cognition in T2D.

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Arterial Wall function is associated with cognitive performance primarily in elderly with type 2 diabetes

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Keywords

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