Approach to Therapy for Chronic Pouchitis

Maia Kayal; Brigid Boland

doi:10.1146/annurev-med-032224-120544

Approach to Therapy for Chronic Pouchitis

Maia Kayal
, Brigid Boland

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Abstract

Chronic pouchitis (CP) occurs in approximately 20% of patients with ulcerative colitis after total proctocolectomy with ileal pouch anal anastomosis and is categorized as antibiotic dependent, antibiotic refractory, or Crohn's disease-like. The management of CP is challenging because of limited evidence and few randomized controlled trials. In this review, we discuss the medical management of CP and its supporting data delineated by type of therapy.

Original language	English
Pages (from-to)	167-173
Number of pages	7
Journal	Annual Review of Medicine
Volume	76
DOIs	https://doi.org/10.1146/annurev-med-032224-120544
State	Published - 27 Jan 2025

Keywords

Crohn's disease
pouchitis
proctocolectomy
ulcerative colitis

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10.1146/annurev-med-032224-120544

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title = "Approach to Therapy for Chronic Pouchitis",

abstract = "Chronic pouchitis (CP) occurs in approximately 20\% of patients with ulcerative colitis after total proctocolectomy with ileal pouch anal anastomosis and is categorized as antibiotic dependent, antibiotic refractory, or Crohn's disease-like. The management of CP is challenging because of limited evidence and few randomized controlled trials. In this review, we discuss the medical management of CP and its supporting data delineated by type of therapy.",

keywords = "Crohn's disease, pouchitis, proctocolectomy, ulcerative colitis",

author = "Maia Kayal and Brigid Boland",

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T1 - Approach to Therapy for Chronic Pouchitis

AU - Kayal, Maia

AU - Boland, Brigid

PY - 2025/1/27

Y1 - 2025/1/27

N2 - Chronic pouchitis (CP) occurs in approximately 20% of patients with ulcerative colitis after total proctocolectomy with ileal pouch anal anastomosis and is categorized as antibiotic dependent, antibiotic refractory, or Crohn's disease-like. The management of CP is challenging because of limited evidence and few randomized controlled trials. In this review, we discuss the medical management of CP and its supporting data delineated by type of therapy.

AB - Chronic pouchitis (CP) occurs in approximately 20% of patients with ulcerative colitis after total proctocolectomy with ileal pouch anal anastomosis and is categorized as antibiotic dependent, antibiotic refractory, or Crohn's disease-like. The management of CP is challenging because of limited evidence and few randomized controlled trials. In this review, we discuss the medical management of CP and its supporting data delineated by type of therapy.

KW - Crohn's disease

KW - pouchitis

KW - proctocolectomy

KW - ulcerative colitis

UR - https://www.scopus.com/pages/publications/85217041492

U2 - 10.1146/annurev-med-032224-120544

DO - 10.1146/annurev-med-032224-120544

M3 - Review article

C2 - 39869428

AN - SCOPUS:85217041492

SN - 0066-4219

VL - 76

SP - 167

EP - 173

JO - Annual Review of Medicine

JF - Annual Review of Medicine

ER -

Approach to Therapy for Chronic Pouchitis

Abstract

Keywords

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