TY - JOUR
T1 - Application of computerized exercise ECG digitization. Interpretation in large clinical trials
AU - Caralis, Dennis G.
AU - Shaw, Leslee
AU - Bilgere, Brian
AU - Younis, Liwa
AU - Stocke, Karen
AU - Wiens, Robert D.
AU - Chaitman, Bernard R.
N1 - Funding Information:
Supported in part by NIH ROI HL42145-03. Bethesda, Maryland and by a grant from the David B. Lichtenstein Foundation, St. Louis, Missouri.
PY - 1992/4
Y1 - 1992/4
N2 - The authors report on a semiautomated program that incorporates both visual identification of fiducial points and digital determination of the ST-segment at 60 ms and 80 ms from the J point, ST slope, changes in R wave, and baseline drift. The off-line program can enhance the accuracy of detecting electrocardiographic (ECG) changes, as well as reproducibility of the exercise and postexercise ECG, as a marker of myocardial ischemia. The analysis program is written in Microsoft QuickBASIC 2.0 for an IBM personal computer interfaced to a Summagraphics mm1201 microgrid II digitizer. The program consists of the following components: (1) alphanumeric data entry, (2) ECG wave form digitization, (2) calculation of test results, (4) physician overread, and (5) editor function for remeasurements. This computerized exercise ECG digitization-interpretation program is accurate and reproducible for the quantitative assessment of ST changes and requires minimal time allotment for physician overread. The program is suitable for analysis and interpretation of large volumes of exercise tests in multicenter clinical trials and is currently utilized in the TIMI II, TIMI III, and BARI studies sponsored by the National Institutes of Health.
AB - The authors report on a semiautomated program that incorporates both visual identification of fiducial points and digital determination of the ST-segment at 60 ms and 80 ms from the J point, ST slope, changes in R wave, and baseline drift. The off-line program can enhance the accuracy of detecting electrocardiographic (ECG) changes, as well as reproducibility of the exercise and postexercise ECG, as a marker of myocardial ischemia. The analysis program is written in Microsoft QuickBASIC 2.0 for an IBM personal computer interfaced to a Summagraphics mm1201 microgrid II digitizer. The program consists of the following components: (1) alphanumeric data entry, (2) ECG wave form digitization, (2) calculation of test results, (4) physician overread, and (5) editor function for remeasurements. This computerized exercise ECG digitization-interpretation program is accurate and reproducible for the quantitative assessment of ST changes and requires minimal time allotment for physician overread. The program is suitable for analysis and interpretation of large volumes of exercise tests in multicenter clinical trials and is currently utilized in the TIMI II, TIMI III, and BARI studies sponsored by the National Institutes of Health.
KW - computer ECG analysis
KW - exercise electrocardiography
KW - exercise testing
UR - https://www.scopus.com/pages/publications/0026579726
U2 - 10.1016/0022-0736(92)90114-F
DO - 10.1016/0022-0736(92)90114-F
M3 - Article
C2 - 1522395
AN - SCOPUS:0026579726
SN - 0022-0736
VL - 25
SP - 101
EP - 110
JO - Journal of Electrocardiology
JF - Journal of Electrocardiology
IS - 2
ER -