TY - JOUR
T1 - Applicability of adult-to-adult living donor liver transplantation
AU - Rimola, Antoni
AU - Llovet, Josep M.
AU - Navasa, Miquel
AU - Bruix, Jordi
AU - Londoño, María Carlota
AU - Fuster, Josep
AU - García-Valdecasas, Juan Carlos
N1 - Funding Information:
This study has been supported in part by the grants C0/02, C03/03 and C03/10 from the Instituto de Salud Carlos III, Spain. JM Lovet is a recipient of a contract from the Programa Ramon y Cajal (IDIBAPS, Ministerio de Ciencia y Tecnologia), AGAUR grants (2003BEA100138 and 2004BE00226, Generalitat de Catalunya) and an Instituto de Salud Carlos III grant (Fondo de Investigaciones Sanitarias 2002–2005, PI02/0596).
PY - 2005/7
Y1 - 2005/7
N2 - Background/Aims: The applicability of adult-to-adult living donor liver transplantation has not been established yet. We report the first data in a European center of the process leading to this procedure from the first moment the patients were informed about it. Methods: In phase 1 of the process, 121 adult patients enlisted for cadaveric liver transplantation and their relatives were informed of the technical aspects, advantages and risks of living donor liver transplantation, and the essential criteria for living donation. In phase 2, potential donors identified in phase 1 were evaluated in depth. Results: Twenty-one (17%) patients underwent living donor liver transplantation. This procedure was not performed in 60 patients (50%) for reasons concerning the patients themselves, especially their refusal to receive living donor liver transplantation from a relative (30%). Forty patients (33%) did not undergo living donor liver transplantation for reasons concerning potential donors: donors were not identified (14%), declined the donation (13%), or were refused for technical reasons (6%). The expected waiting time to transplantation was longer in patients who underwent living donor liver transplantation than in those who did not. Conclusions: The applicability of adult-to-adult living donor liver transplantation is low, mainly because of reasons related to potential recipients.
AB - Background/Aims: The applicability of adult-to-adult living donor liver transplantation has not been established yet. We report the first data in a European center of the process leading to this procedure from the first moment the patients were informed about it. Methods: In phase 1 of the process, 121 adult patients enlisted for cadaveric liver transplantation and their relatives were informed of the technical aspects, advantages and risks of living donor liver transplantation, and the essential criteria for living donation. In phase 2, potential donors identified in phase 1 were evaluated in depth. Results: Twenty-one (17%) patients underwent living donor liver transplantation. This procedure was not performed in 60 patients (50%) for reasons concerning the patients themselves, especially their refusal to receive living donor liver transplantation from a relative (30%). Forty patients (33%) did not undergo living donor liver transplantation for reasons concerning potential donors: donors were not identified (14%), declined the donation (13%), or were refused for technical reasons (6%). The expected waiting time to transplantation was longer in patients who underwent living donor liver transplantation than in those who did not. Conclusions: The applicability of adult-to-adult living donor liver transplantation is low, mainly because of reasons related to potential recipients.
KW - Cadaveric liver transplantation
KW - Living donor liver transplantation
KW - Waiting list
UR - https://www.scopus.com/pages/publications/20444420113
U2 - 10.1016/j.jhep.2005.02.016
DO - 10.1016/j.jhep.2005.02.016
M3 - Article
C2 - 15876470
AN - SCOPUS:20444420113
SN - 0168-8278
VL - 43
SP - 104
EP - 109
JO - Journal of Hepatology
JF - Journal of Hepatology
IS - 1
ER -