Appearance of acute gouty arthritis on indium-111-labeled leukocyte scintigraphy

C. J. Palestro, A. Vega, C. K. Kim, A. J. Swyer, S. J. Goldsmith

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


Indium-111-labeled leukocyte scintigraphy was performed on a 66-yr-old male with polyarticular acute gouty arthritis. Images revealed intense labeled leukocyte accumulation in a pattern indistinguishable from septic arthritis, in both knees and ankles, and the metatarsophalangeal joint of both great toes, all of which were involved in the acute gouty attack. Joint aspirate as well as blood cultures were reported as no growth; the patient was treated with intravenous colchicine and ACTH for 10 days with dramatic improvement noted. Labeled leukocyte imaging, repeated 12 days after the initial study, revealed near total resolution of joint abnormalities, concordant with the patient's clinical improvement. This case demonstrates that while acute gouty arthritis is a pitfall in labeled leukocyte imaging, in the presence of known gout, it may provide a simple, objective, noninvasive method of evaluating patient response to therapy.

Original languageEnglish
Pages (from-to)682-687
Number of pages6
JournalJournal of Nuclear Medicine
Issue number5
StatePublished - 1990


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