Apoptosis: Stabbed in the BAX

Douglas R. Green, Jerry E. Chipuk

Research output: Contribution to journalShort surveypeer-review

47 Scopus citations

Abstract

Apoptotic cell death is an intricate and highly regulated process. To initiate apoptosis, the protein BIM binds to a hitherto unrecognized site on the BAX protein to trigger permeabilization of the outer mitochondrial membrane.

Original languageEnglish
Pages (from-to)1047-1049
Number of pages3
JournalNature
Volume455
Issue number7216
DOIs
StatePublished - 23 Oct 2008
Externally publishedYes

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