Apomorphine has no effect on plasma homovanillic acid in schizophrenic patients

Michael Davidson; Kenneth S. Kendler; Bonnie M. Davis; Thomas B. Horvath; Richard C. Mohs; Kenneth L. Davis

doi:10.1016/0165-1781(85)90002-2

Apomorphine has no effect on plasma homovanillic acid in schizophrenic patients

Michael Davidson, Kenneth S. Kendler, Bonnie M. Davis, Thomas B. Horvath, Richard C. Mohs, Kenneth L. Davis

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Previous experiments suggest that pharmacological perturbations of the brain dopaminergic system may be reflected by concentrations of plasma homovanillic acid. This study examined the ability of low-dose apomorphine to reduce plasma homovanillic acid concentrations in schizophrenic patients chronically treated with neuroleptics. The data suggest that apromorphine dose not reduced plasma homovanillic acid in those patients.

Original language	English
Pages (from-to)	95-99
Number of pages	5
Journal	Psychiatry Research
Volume	16
Issue number	2
DOIs	https://doi.org/10.1016/0165-1781(85)90002-2
State	Published - Oct 1985
Externally published	Yes

Keywords

Homovanillic acid
apomorphine
schizophrenia

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10.1016/0165-1781(85)90002-2

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title = "Apomorphine has no effect on plasma homovanillic acid in schizophrenic patients",

abstract = "Previous experiments suggest that pharmacological perturbations of the brain dopaminergic system may be reflected by concentrations of plasma homovanillic acid. This study examined the ability of low-dose apomorphine to reduce plasma homovanillic acid concentrations in schizophrenic patients chronically treated with neuroleptics. The data suggest that apromorphine dose not reduced plasma homovanillic acid in those patients.",

keywords = "Homovanillic acid, apomorphine, schizophrenia",

author = "Michael Davidson and Kendler, {Kenneth S.} and Davis, {Bonnie M.} and Horvath, {Thomas B.} and Mohs, {Richard C.} and Davis, {Kenneth L.}",

note = "Funding Information: Acknowledgments. This work, was supported by two grants from the Veterans Administration, SBRC grant number 4125-019,G eneral Medical Research grant number 4125-021, and National Institute of Mental Health grant number MH-37922.",

year = "1985",

month = oct,

doi = "10.1016/0165-1781(85)90002-2",

language = "English",

volume = "16",

pages = "95--99",

journal = "Psychiatry Research",

issn = "0165-1781",

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TY - JOUR

T1 - Apomorphine has no effect on plasma homovanillic acid in schizophrenic patients

AU - Davidson, Michael

AU - Kendler, Kenneth S.

AU - Davis, Bonnie M.

AU - Horvath, Thomas B.

AU - Mohs, Richard C.

AU - Davis, Kenneth L.

N1 - Funding Information: Acknowledgments. This work, was supported by two grants from the Veterans Administration, SBRC grant number 4125-019,G eneral Medical Research grant number 4125-021, and National Institute of Mental Health grant number MH-37922.

PY - 1985/10

Y1 - 1985/10

N2 - Previous experiments suggest that pharmacological perturbations of the brain dopaminergic system may be reflected by concentrations of plasma homovanillic acid. This study examined the ability of low-dose apomorphine to reduce plasma homovanillic acid concentrations in schizophrenic patients chronically treated with neuroleptics. The data suggest that apromorphine dose not reduced plasma homovanillic acid in those patients.

AB - Previous experiments suggest that pharmacological perturbations of the brain dopaminergic system may be reflected by concentrations of plasma homovanillic acid. This study examined the ability of low-dose apomorphine to reduce plasma homovanillic acid concentrations in schizophrenic patients chronically treated with neuroleptics. The data suggest that apromorphine dose not reduced plasma homovanillic acid in those patients.

KW - Homovanillic acid

KW - apomorphine

KW - schizophrenia

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U2 - 10.1016/0165-1781(85)90002-2

DO - 10.1016/0165-1781(85)90002-2

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VL - 16

SP - 95

EP - 99

JO - Psychiatry Research

JF - Psychiatry Research

IS - 2

ER -

Apomorphine has no effect on plasma homovanillic acid in schizophrenic patients

Abstract

Keywords

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